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Ko, Jeong-Hyeon, et al
Senolytic FOXO4-DRI can inhibit FOXO4 binding by disrupting the p53-FOXO4 interaction and selectively cause apoptosis via p53 nuclear exclusion in senescent cells and aging mouse models, which may be a promising approach for preventing senescence 11
Despite this, a comprehensive understanding of these pathways is lacking, driving the search for more effective management strategies for APAP hepatotoxicity
If the liver produces enough glutathione, it can exit acetaldehyde (alcohol turned into toxic acid in the liver) quickly from the body
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